Have you been looking for a way to replace all instances of notepad.exe on Windows Server 2008? If so, here is a quick and dirty batch file to help you out.

Note: I ran a "dir /s /b notepad.exe > replace_notepad.cmd" to get a list of copies of notepad.exe on the c drive, then edited the new file with what is below

@echo off 
echo Create Backup copies of the original notepad.exe 
copy C:\Windows\notepad.exe C:\Windows\notepad32.exe 
copy C:\Windows\System32\notepad.exe C:\Windows\System32\notepad32.exe
copy C:\Windows\SysWOW64\notepad.exe C:\Windows\SysWOW64\notepad32.exe

echo Take Ownership of the files rem This could be changed to use icacls now 
takeown /F C:\Windows\notepad.exe /A 
takeown /F C:\Windows\System32\notepad.exe /A 
takeown /F C:\Windows\SysWOW64\notepad.exe /A
takeown /F C:\Windows\winsxs\x86_microsoft-windows-notepadwin_31bf3856ad364e35_6.0.6001.18000_none_42c9ccdefb0d0dc9\notepad.exe /A 
takeown /F C:\Windows\winsxs\x86_microsoft-windows-notepad_31bf3856ad364e35_6.0.6001.18000_none_6f1a8d7b6fffbb73\notepad.exe /A 

takeown /F C:\Windows\winsxs\amd64_microsoft-windows-notepadwin_31bf3856ad364e35_6.1.7600.16385_none_9ebebe8614be1470\notepad.exe /A
takeown /F C:\Windows\winsxs\amd64_microsoft-windows-notepad_31bf3856ad364e35_6.1.7600.16385_none_cb0f7f2289b0c21a\notepad.exe /A
takeown /F C:\Windows\winsxs\wow64_microsoft-windows-notepad_31bf3856ad364e35_6.1.7600.16385_none_d5642974be118415\notepad.exe /A

echo Assign full rights to the administrators group 
icacls c:\windows\notepad.exe /grant Administrators:F 
icacls C:\Windows\System32\notepad.exe /grant Administrators:F
icacls C:\Windows\SysWOW64\notepad.exe /grant Administrators:F
icacls C:\Windows\winsxs\x86_microsoft-windows-notepadwin_31bf3856ad364e35_6.0.6001.18000_none_42c9ccdefb0d0dc9\notepad.exe /grant Administrators:F 
icacls C:\Windows\winsxs\x86_microsoft-windows-notepad_31bf3856ad364e35_6.0.6001.18000_none_6f1a8d7b6fffbb73\notepad.exe /grant Administrators:F 

icacls C:\Windows\winsxs\amd64_microsoft-windows-notepadwin_31bf3856ad364e35_6.1.7600.16385_none_9ebebe8614be1470\notepad.exe /grant Administrators:F 
icacls C:\Windows\winsxs\amd64_microsoft-windows-notepad_31bf3856ad364e35_6.1.7600.16385_none_cb0f7f2289b0c21a\notepad.exe /grant Administrators:F 
icacls C:\Windows\winsxs\wow64_microsoft-windows-notepad_31bf3856ad364e35_6.1.7600.16385_none_d5642974be118415\notepad.exe /grant Administrators:F 

echo Copy new notepad.exeover the original versions 
copy /y C:\notepad.exe C:\Windows\notepad.exe 
copy /y C:\notepad.exe C:\Windows\System32\notepad.exe 
copy /y C:\notepad.exe C:\Windows\SysWOW64\notepad.exe
copy /y C:\notepad.exe C:\Windows\winsxs\x86_microsoft-windows-notepadwin_31bf3856ad364e35_6.0.6001.18000_none_42c9ccdefb0d0dc9\notepad.exe
copy /y C:\notepad.exe C:\Windows\winsxs\x86_microsoft-windows-notepad_31bf3856ad364e35_6.0.6001.18000_none_6f1a8d7b6fffbb73\notepad.exe

copy /y C:\notepad.exe C:\Windows\winsxs\amd64_microsoft-windows-notepadwin_31bf3856ad364e35_6.1.7600.16385_none_9ebebe8614be1470\notepad.exe
copy /y C:\notepad.exe C:\Windows\winsxs\amd64_microsoft-windows-notepad_31bf3856ad364e35_6.1.7600.16385_none_cb0f7f2289b0c21a\notepad.exe
copy /y C:\notepad.exe C:\Windows\winsxs\wow64_microsoft-windows-notepad_31bf3856ad364e35_6.1.7600.16385_none_d5642974be118415\notepad.exe